Temporal Sepsis Modeling: a Relational and Explainable-by-Design Framework
Quick summary
arXiv:2601.21747v4 Announce Type: replace-cross Abstract: Sepsis remains one of the most complex and heterogeneous syndromes in intensive care. While deep learning models achieve competitive performance in early sepsis prediction, their decision processes often remain difficult to interpret clinically, and explainability is typically added only through post-hoc methods. We propose an explainable-by-design framework based on a relational approach: temporal EHR data are represented in a relational schema, flattened via MDL-based propositionalisation into compact human-readable features, and clas
Key takeaways
- arXiv:2601.21747v4 Announce Type: replace-cross Abstract: Sepsis remains one of the most complex and heterogeneous syndromes in intensive care.
- While deep learning models achieve competitive performance in early sepsis prediction, their decision processes often remain difficult to interpret clinically, and explainability is typically added only through post-hoc methods.
- We propose an explainable-by-design framework based on a relational approach: temporal EHR data are represented in a relational schema, flattened via MDL-based propositionalisation into compact human-readable features, and clas
Why it matters
“Temporal Sepsis Modeling: a Relational and Explainable-by-Design Framework” illustrates how changes in the AI ecosystem can affect products, workflows and user expectations together. Its lasting significance depends on measurable adoption, cost and safety outcomes.

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